Guidelines summarize the research and translate it into treatment recommendations. The quality of evidence and the strength of a recommendation are not the same thing. Grade A (“shall”) indicates a strong recommendation, while Grade B (“should”) indicates a recommendation. In addition to the available studies, factors such as benefits, risks, clinical experience, and patient preferences are taken into account.
Randomized controlled trials are particularly important for assessing efficacy. Random assignment reduces systematic differences between groups, but does not eliminate every possible source of bias.
Depression. The National Disease Management Guideline for Unipolar Depression, Version 3.2 from July 2023, does not favor one approach over another: “To date, there is no evidence on the differential indication of specific approaches for specific patients with depressive disorders.” This is not a free pass, since the guideline itself adds the caveat: “However, not every approach is equally suitable for every patient,” and a wrong choice could also lead to a worsening. A lack of evidence does not mean that the choice does not matter. According to Recommendation 4-27, the choice belongs in the consultation or the trial sessions.
Anxiety. For anxiety disorders, CBT is the firm first choice: first-line treatment with the highest grade of recommendation. That is what it says in the S3 guideline on the treatment of anxiety disorders, Version 2.0 dated April 6, 2021: “Cognitive behavioral therapy (CBT) shall be offered (Ia/A).” Psychodynamic treatment follows, with grade of recommendation B and subject to one condition: it should be offered “if CBT has not proved effective, is not available, or if the informed patient has a preference for it.” This applies, with identical wording, to panic disorder and agoraphobia, generalized anxiety disorder, and social phobia. Regarding generalized anxiety disorder, the guideline is clear: “Psychodynamic therapy appears to be inferior to CBT.” The guideline’s own addendum belongs in the same place: “The available studies were conducted over up to 30 hours.”
OCD. For obsessive-compulsive disorders, this very evidence is lacking. Statement 4-21 of the S3 guideline on obsessive-compulsive disorder, Version 2.0 dated June 30, 2022, states: “There is no evidence from randomized controlled trials for the effectiveness of these approaches.” Recommendation 4-1, Grade A: “For obsessive-compulsive disorder, disorder-specific cognitive behavioral therapy (CBT), including exposure, shall be offered as first-line psychotherapy.”
The first-line treatment in accordance with the guidelines therefore remains disorder-specific CBT, including exposure. I have also treated people with obsessive-compulsive disorder using psychodynamic approaches, but I have never presented this approach as being equally well-supported. Understanding individual fears, conflicts, and relationship patterns can be helpful; however, it does not replace transparent information about the more well-established treatment of obsessive-compulsive symptoms.
In the standard textbook of my approach, Michael Ermann cites, in addition to the early developmental disorder, a genetic predisposition and involvement of the frontal lobe, basal ganglia, and limbic system. He also writes that obsessive-compulsive disorders are chronic, do not resolve spontaneously, and are extremely difficult to treat.
PTSD. The S3 guideline on post-traumatic stress disorder, in the version of February 27, 2026, recommends, with Grade A, a trauma-focused approach in an individual setting and lists five interventions with solid evidence, including Eye Movement Desensitization and Reprocessing (EMDR). Psychodynamic approaches are mentioned only in the research recommendations and among the approaches whose effectiveness has not been sufficiently tested. However, many practitioners across all disciplines have additional training in trauma therapy approaches.